Best Ergonomic Mouse for Big Hands

Reviewed by Betsy Sanchez
Betsy Sanchez

Betsy Sanchez is a professional graphic designer with over 10 years of experience. She loves all things tech and that's why she started writing on different topics online now here, working with us to help the audience who are looking for perfect comfort.

Best Ergonomic Mouse for Big Hands

These days, most of the work is done behind the screen. “You have to have industry standard equipment while working in order to maintain your productivity”.

People often link the equipment’s quality with productivity, to some extent, we also agree with it but what if you buy the best mouse for yourself and it doesn’t feel right in your hand? You won’t be able to work right?

Along with product quality, its dimensions also play a vital role in enhancing productivity.

In this guide, since we are discussing ergonomic mice for big hands, it is likely that you are not comfortable with your current mouse. If it is true, we would strongly recommend you replace the mouse as soon as possible.

Using a too small or too big mouse can degrade your productivity, and increases the chance of wrist injury and muscle fatigue.

Quick Tip: You must not put effort into holding your mouse, it should align automatically with your hand size, and your palm must be resting on it not squeezing it.

Today, we are going to discuss the followings:

Before jumping on the list, let’s quickly understand, how to measure hand size:

How to Measure Hand Size for Mouse

Identifying whether your hand is small or big is no rocket science. You can measure your hand within a minute, just follow the steps mentioned below:

Step 1: Place your hand upside down (palm facing the roof) on a flat surface.

Step 2: Measure the distance between your longest finger (middle finger) and wrist crease.

That’s it! Now you have a measurement of your hand.

Do you really have big hands?

It’s time to check in which category your hand falls under, refer to the table attached below:

Hand MeasurementHand Size CategorySuitable Mouse Size
Less than 17.1 cmSmallSmall
Between 17.1 cm and 19.3 cmAverageNormal
More than 19.3 cmBigLarge

This measurement table is suggested after a study done by the HealthLine portal. Besides this, the table is applicable to both males and females.

We are done with all the prerequisites, let’s begin with the list of the best mice for big hands:

1. iClever Ergonomic Mouse – Wireless Vertical Mouse

iClever Ergonomic Mouse

iClever has never disappointed us with its products, Again for big hands, iClever presents this outstanding wireless vertical mouse.

In this mouse, you get a unique cavity design that enhances the overall ergonomics of this mouse. While holding this mouse, you won’t have to grip it, its carefully crafted design syncs perfectly with your palm and fingers.

The vertical design ensures that your hand stays in a natural position throughout usage. On top of this, in the palm resting area, you get a diamond pattern that not only enhances the looks of mice but also ensures that your palm doesn’t get sweaty even after using it for hours.

You get 3 customizable DPI resolutions, even while sliding the mouse, your cursor won’t shake.

For easy web browsing and multi-tasking, the mouse has 2 additional forward and backward buttons placed right above the thumb rest for easy accessibility.


  • Length: 13.8 cm
  • Width: 6.8 cm
  • Height: 7.5 cm
  • Weight: 108 g

Since the device is completely wireless, your desk aesthetics won’t be disturbed and you can simply plug the USB receiver in and use the mice. With the 2.4 GHz wireless technology, you get a connection range of 33 feet.

In case you are looking for a silent mouse, we would say, skip the other products on this list and buy this mouse. It comes with whisper-quiet technology, therefore you can work inside your bedroom without disturbing anyone’s sleep.

At the bottom of the mouse, you get a AA Battery Slot, an On/OFF switch, and a dedicated receiver slot. For power efficiency, this iClever vertical wireless mouse comes with Auto-Power Save capability, in this technology, the device goes to sleep after 10 minutes of being idle and turns itself back as soon as the user interacts with it.

Customers have reported that even after using the mouse for a whole day, they don’t feel any pain or numbness in their wrists. You also get a 1 year of limited warranty from the manufacturer.

Overall, you can’t get yourself a better mouse than the iClever vertical wireless mouse under its price bracket.


  • Whisper Quiet Technology
  • Diamond Design
  • Auto-Power Saving
  • Precise Tracking


  • No-built in rechargeable battery
  • Less DPI customization options

2. SteelSeries Sensei 310 Gaming Mouse

SteelSeries Sensei 310 Gaming Mouse

If you are looking for a gaming mouse that could sit perfectly in your big hands, SteelSeries Sensei 310 is the best suitable option. It’s a wired mouse, therefore, no latency-related issues during gaming.

With this mouse, you get a TrueMove3 Sensor that ensures minimum latency, rapid-response tracking, and precise mouse movements. The True 1-to-1 tracking technology and Jitter Reduction mechanism ensure natural mouse movement with almost zero hindrances.

The Ambidextrous design of this mouse offers maximum comfort and flexibility. The durable silicon grip at the sides offers a premium feel.

For a better gaming experience, you get 4 trigger buttons, 2 on each side. You can customize every button of this mouse as per your requirements. You also get 5 levels of CPI (or DPI) customization options.


  • Length: 12.4 cm
  • Width: 7.1 cm
  • Height: 3.8 cm
  • Weight: 92.1 g

As mentioned above, this mouse weighs only 92.1g. The lightweight weight construction makes the maneuvering of the mice quite fast and easy. To enhance the gaming experience, SteelSeries offers a spectrum of 16.8 million colors in Prism RGB lighting.

Besides this, RGB lightning responds to events in the game like low ammunition, critical health, and many more.

This mouse is compatible with both Windows and macOS. To customize the buttons, you can use SteelSeries Engine software.


  • Durable Mesh USB A Cable
  • 4 Side Trigger Buttons
  • Premium Build
  • Responsive Prism RGB lightning


  • No Wireless Option

3. Razer Basilisk V3

Razer Basilisk V3

Here we present another super powerful gaming mouse for big hands. Razer is known for its premium gaming products.

Razer Basilisk V3 is one of the most premium gaming mouse, you can get for yourself. On this mouse, you get 11 different RGB lightning zones where you can select your desired RGB color from 16.8 million color options.

Besides this, you get a total of 11 fully programmable buttons, as per your gaming requirements, you can set the actions on different buttons.

This Razer mouse has a 26k DPI optical sensor that ensures flawless tracking of movements and pixel-precise accuracy.


  • Length: 13 cm
  • Width: 7.5 cm
  • Height: 4.2 cm
  • Weight: 101 g

Even the scroll wheel (HyperScroll wheel) of Razer Basilisk V3 is loaded with a lot of features, one of them is a friction-free scroll. While switching weapons, you can spin the wheel and it will scroll until you stop it.

Over a million users trust this mouse, thanks to its ultra-premium material and build quality. On this gaming mouse, you have a dedicated thumb rest that offers a super comfortable grip.

Every button on this mouse is positioned so precisely that you won’t feel any fatigue even after hours of gaming.

Since it’s a USB device, it offers ultra-low latency and lag while gaming. Besides all this, you get a 1 year of limited warranty.

If you have a premium budget and need a gaming mouse, you must go for the Razer Basilisk V3 mouse.


  • HyperScroll Wheel
  • 11 Programmable Buttons
  • 11 RGB lighting zones
  • Premium 26K DPI Optical Sensor


  • No wireless option is available

4. Lekvey Wireless Left Hand Vertical Mouse

Lekvey Wireless Left Hand Vertical Mouse

This mouse is specially designed for left-hand users, you can’t get a better option than Lekvey wireless vertical mouse.

The design of this mouse ensures that your hand stays in a natural, relaxed position and your wrist doesn’t undergo any strain. Even after using this mouse for hours, you won’t feel any fatigue and stiffness of muscles near the wrist.

With the 2.4 GHz wireless connectivity, you can simply plug and play. However, you must note that this mouse is not compatible with macOS.

Other than the basic 4 buttons, you get two extra forward and backward buttons situated on the right side of the mouse, just above the thumb rest.


  • Length: 12.7 cm
  • Width: 6.3 cm
  • Height: 7.6 cm
  • Weight: 95 g

For easy web browsing, there are three-level DPI options available. The advanced sensor tracks movements precisely.

In order to power the device, you will need 2 AAA batteries, kindly note that batteries are not included in the package. For better efficiency, it comes with a power-saving mode, which enables it to go into sleep mode if left idle for more than 8 minutes. To wake up the device, you can press either the right or left button.

This mouse is compatible with both Windows and Linux and other devices except MacOS. Besides that, you get 2 years of limited warranty.


  • Specially designed for Left-handed users
  • 2 Years of Limited Warranty
  • Lightweight
  • Additional 4 buttons for easy web browsing
  • Power Saving mode


  • Not compatible with macOS
  • No built-in rechargeable battery

5. Kensington Ergonomic Vertical Wireless Mouse

Kensington Ergonomic Vertical Wireless Mouse

If you are looking for a solid-built budget vertical mouse with all the basic features, this Kensington vertical mouse could be a good option for you.

Apart from the conventional Right and Left buttons, you get two forward and backward buttons for easy web browsing. The extra smooth scroll wheel offers decent scrolling on web pages and documents.

Since it’s a 2.4GHz wireless mouse, you get a connection range of 33 feet, and to power the device, you will need a AA battery. For better power efficiency, it has an Auto-Sleep function.

This power-saving method enables the mouse to go into Sleep mode if left idle for 10 minutes. Whenever the user interacts with the mice, it turns back on.

You can simply plug and play the device either on a Windows or macOS machine. You will find the nano receiver at the bottom of the mice.

The vertical design ensures that your hand stays in a neutral handshake position and even after hours of usage, you won’t feel strain in your wrist or hand.


  • Length: 11.1 cm
  • Width: 7.2 cm
  • Height: 7 cm
  • Weight: 95 g

This mouse has 5 different DPI levels that you can adjust as per your requirements using a dedicated DPI Button. Also note that, in the box itself, you get a AA battery.

This mouse is also compatible with extra large hands as well, thanks to the dedicated pinky finger rest.


  • Dedicated Pinky Finger Rest
  • Vertical Ergonomic Design
  • 5 Customizable DPI Options
  • Additional Forward and Backward Buttons
  • Smooth Scroll Wheel


  • No built-in rechargeable battery


Working behind the screen with the wrong types of equipment could affect your productivity adversely.

If you are using a normal mouse despite having big hands, you will gradually see a downfall in your productivity and could suffer from wrist injuries.

But since you have gone through our list now, you won’t have to struggle while using your mouse. You can pick any one of the above-listed ergonomic mice designed especially for big hands.

From the above list, our personal favorite is Razer Basilisk V3. In case you have extra large hands, we would recommend the iClever Ergonomic Mouse. Its diamond design offers extreme comfort during long working hours and prevents sweating in the palm.

Apart from this, if you have some product suggestions for us, do let us know in the comments below.

We hope, after reading this guide, you will find your perfect mouse. Do share it with your friends and help them find their ideal mouse.